Question Comments on Indian Study on preventing covid-19

Jul 2, 2020
76
3
55
Results from Vadodara in India of Hydroxychloroquine HCQ given for up to 3 weeks to 100,000 high risk non infected/asymptomatic people who had close contact with a covid-19 infected person show

After 1 week of HCQ treatment
100 infections and
12 deaths
After 2 weeks of HCQ treatment there were
48 infections
1 death
After3 weeks of HCQ treatment there were
43 infections
1 death

[it is reported that approx 50,000 had 1 week of HCQ and 50,000 2-3 weeks of HCQ treatment]

These look very positive results with no real side effects reported

This is a big observational report, it is unclear what conflicts of interest etc may be present but if the data is reliable it is very positive.

These findings were supported by a later studies published in the IJMR for a smaller group of health care workers treated for 6 weeks. Reservations were expressed that there may be a conflict as those conducting the IJMR study had been involved in approving the use of HCQ for treating Covid-19




Healthcare workers & SARS-CoV-2 infection in India: A case-control investigation in the time of COVID-19 Chatterjee P, Anand T, Singh KJ, Rasaily R, Singh R, Das S, Singh H, Praharaj I, Gangakhedkar RR, Bhargava B, Panda S - Indian J Med Res
Indian J Med Res, Official publication of Indian Council of Medical Research,India

www.ijmr.org.in







pubmed.ncbi.nlm.nih.gov


Healthcare workers & SARS-CoV-2 infection in India: A case-control investigation in the time of COVID-19 - PubMed
Until results of clinical trials for HCQ prophylaxis become available, this study provides actionable information for policymakers to protect HCWs at the forefront of COVID-19 response. The public health message of sustained intake of HCQ prophylaxis as well as appropriate PPE use need to be...

pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov




Vadodara Health Officer Dr Devesh Patel is quoted as saying "HCQ has not been used as a prophylactic… To us, it has shown positive results. We have the numbers"




indianexpress.com


Vadodara administration drive: HCQ helping in containing Covid-19 cases, say docs as analysis begins
Authorities say that the analysis is ongoing as is the drive, in accordance with the ICMR recommendation for prophylactic use of HCQ. VMC Health Officer Dr Devesh Patel says, “The debate around HCQ is founded in the side effects of long term use of the drug for treatment of rheumatoid arthritis...

indianexpress.com
indianexpress.com




In India HCQ has been used extensively as a prophylatic outside the hospital setting to give protection to those at high risk. The reports provided from the area of Vadodara of the end of June were that around 350,000 high risk people had received HCQ and 100,000 of those had been closely monitored.

The treatment was 400mg taken twice on the first day and 400 mg per week for between one to three weeks.

Results the 100,000 monitored all had close contact with an infected person.

A. 48,873 who took one dose of HCQ, 102 turned Covid-19 positive and 12 died
B. 17,776 who took two doses of HCQ 48 turned positive and 1 died.
C. 33,563 who took three HCQ doses, 43 tested positive and 1 died.




www.newindianexpress.com


Six or more dosages of HCQ reduce Covid-19 risk in health workers: IMCR study
The study has, however, drawn flak for not coming clean on the issue of “conflict of interest".

www.newindianexpress.com
www.newindianexpress.com







medicaldialogues.in


New Guideline: ICMR expands use of Hydroxychloroquine, adds ECG as prerequisite, Details
New Delhi: Expanding the use of anti-malarial drug hydroxychloroquine as a preventive treatment against coronavirus, the ICMR has issued new set of guidelines that also call for proper...

medicaldialogues.in
medicaldialogues.in
 
Last edited:

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Aug 16, 2020
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Results from Vadodara in India of Hydroxychloroquine HCQ given for up to 3 weeks to 100,000 high risk non infected/asymptomatic people who had close contact with a covid-19 infected person show

After 1 week of HCQ treatment
100 infections and
12 deaths
After 2 weeks of HCQ treatment there were
48 infections
1 death
After3 weeks of HCQ treatment there were
43 infections
1 death

[it is reported that approx 50,000 had 1 week of HCQ and 50,000 2-3 weeks of HCQ treatment]

These look very positive results with no real side effects reported

This is a big observational report, it is unclear what conflicts of interest etc may be present but if the data is reliable it is very positive.

These findings were supported by a later studies published in the IJMR for a smaller group of health care workers treated for 6 weeks. Reservations were expressed that there may be a conflict as those conducting the IJMR study had been involved in approving the use of HCQ for treating Covid-19




Healthcare workers & SARS-CoV-2 infection in India: A case-control investigation in the time of COVID-19 Chatterjee P, Anand T, Singh KJ, Rasaily R, Singh R, Das S, Singh H, Praharaj I, Gangakhedkar RR, Bhargava B, Panda S - Indian J Med Res
Indian J Med Res, Official publication of Indian Council of Medical Research,India

www.ijmr.org.in







pubmed.ncbi.nlm.nih.gov


Healthcare workers & SARS-CoV-2 infection in India: A case-control investigation in the time of COVID-19 - PubMed
Until results of clinical trials for HCQ prophylaxis become available, this study provides actionable information for policymakers to protect HCWs at the forefront of COVID-19 response. The public health message of sustained intake of HCQ prophylaxis as well as appropriate PPE use need to be...

pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov




Vadodara Health Officer Dr Devesh Patel is quoted as saying "HCQ has not been used as a prophylactic… To us, it has shown positive results. We have the numbers"




indianexpress.com


Vadodara administration drive: HCQ helping in containing Covid-19 cases, say docs as analysis begins
Authorities say that the analysis is ongoing as is the drive, in accordance with the ICMR recommendation for prophylactic use of HCQ. VMC Health Officer Dr Devesh Patel says, “The debate around HCQ is founded in the side effects of long term use of the drug for treatment of rheumatoid arthritis...

indianexpress.com
indianexpress.com




In India HCQ has been used extensively as a prophylatic outside the hospital setting to give protection to those at high risk. The reports provided from the area of Vadodara of the end of June were that around 350,000 high risk people had received HCQ and 100,000 of those had been closely monitored.

The treatment was 400mg taken twice on the first day and 400 mg per week for between one to three weeks.

Results the 100,000 monitored all had close contact with an infected person.

A. 48,873 who took one dose of HCQ, 102 turned Covid-19 positive and 12 died
B. 17,776 who took two doses of HCQ 48 turned positive and 1 died.
C. 33,563 who took three HCQ doses, 43 tested positive and 1 died.




www.newindianexpress.com


Six or more dosages of HCQ reduce Covid-19 risk in health workers: IMCR study
The study has, however, drawn flak for not coming clean on the issue of “conflict of interest".

www.newindianexpress.com
www.newindianexpress.com







medicaldialogues.in


New Guideline: ICMR expands use of Hydroxychloroquine, adds ECG as prerequisite, Details
New Delhi: Expanding the use of anti-malarial drug hydroxychloroquine as a preventive treatment against coronavirus, the ICMR has issued new set of guidelines that also call for proper...

medicaldialogues.in
medicaldialogues.in
10,000 Indians die every year from cobra bites because they are too dumb to wear boots. So why would I listen to an Indian too dumb to wear shoes
 

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