SARS-CoV-2 relative found lurking in frozen bats from Cambodia

Jul 27, 2020
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More evidence they need to ban exotic wild life consumption.

The mutation rate in this virus is relatively high. An article (1) from the nih.gov website indicates that the spike protein alone has undergone over 8000 mutations (since the date of this publication's sequence availability). There are many more by now.

The article indicates that some of the mutations which might occur in the receptor binding domain (RBD) of the spike protein are more likely to increase its infectivity. Moreover, the mutation rate in the RBD appears to occur at a higher rate than other mutations in the spike protein.

The take home message is that the more this virus spreads, the more infective it appears to become. While this is not yet confirmed, it is certainly a good reason to limit its replication. Faster spread means more misery and potentially more lethal strains developing.

People need to appreciate that this is much more than just about the current rate of infection, and its associated mortality and morbidity. The higher mutation rate may be helping to derive strains with a greater rate of infectivity and mortality. One shouldn't need much schooling to know that is not a good thing.

Everyone should do whatever they can to eliminate these mutants!


"Mutations Strengthened SARS-CoV-2 Infectivity"

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375973/
 
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