Some viruses, such as the human immunodeficiency virus (
HIV) and the chickenpox virus, can integrate themselves into the host genome by making their way into the nucleus of human cells . . .
Although some Herpesviruses integrate into the genome:
Herpesviruses and Chromosomal Integration
Guillaume Morissette, Louis Flamand
Journal of Virology Nov 2010, 84 (23) 12100-12109; DOI: 10.1128/JVI.01169-10
There is no evidence that the chickenpox virus integrates into the host genome.
The chicken pox virus enters into the nucleus, but achieves latency by maintaining a circular episome in the nucleus of the cell.
Sources:
Eshleman, E., Shahzad, A., & Cohrs, R. J. (2011). Varicella zoster virus latency.
Future virology,
6(3), 341–355.
https://doi.org/10.2217/fvl.10.90
Herpesviral Latency—Common Themes
Pathogens 2020,
9(2), 125;
https://doi.org/10.3390/pathogens9020125
Latency establishment is the hallmark feature of herpesviruses, a group of viruses, of which nine are known to infect humans. They have co-evolved alongside their hosts, and mastered manipulation of cellular pathways and tweaking various processes to their advantage. As a result, they are very...
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