Moderna coronavirus vaccine is 94.5% effective, early results suggest

Jul 27, 2020
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Moderna's announcement makes three vaccines claiming 90% or better efficacy.

With Pfizer's RNA vaccine reported at ca. 95% efficacy, and China's vaccine based on inactivated virus reported at ca. 90% efficacy, it would appear that a shortage of effective vaccines will not be an issue. What might be an issue is which vaccine to take!

While the Chinese vaccine may not gain FDA approval in the U.S. due to considerations over trial issues, we still have at least two major vaccines waiting for results - the Johnson and Johnson vaccine, and the Oxford-AstraZeneca adenovirus-based vaccine. (We are also waiting to hear about Sputnik V, the Russian vaccine. )

Moderna clearly has a big edge over the Pfizer vaccine if the quote below from the related article is correct:

"Pfizer and Moderna's vaccines, both given in two doses, seem to be similar in safety and efficacy. But Pfizer's vaccine needs to be stored in ultra-cold temperatures of minus 94 degrees Fahrenheit (minus 70 degrees Celsius), whereas Moderna's needs to be stored at minus 4 F (minus 20 C).

Moderna's vaccine remains stable for up to six months at that temperature, up to 30 days at refrigerated conditions of 36 F to 46 F (2 C to 8 C) and up to 12 hours at room temperature the company said in a separate statement released today. In contrast, Pfizer's vaccine lasts for five days in refrigerated conditions (such as those commonly available in hospitals), according to Reuters."

end quote.

Does anyone have any other vaccine candidates that are likely to work as well? It is beginning to look like all of them will have pretty high efficacy. But there is no hard data on the appearance of ADE, so we have a ways to go before we can all feel better about these vaccines. But it must be said - so far, so good!
 
Last edited:
Jul 2, 2020
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There were a range of coronavirus vaccines for animals successfully developed and being worked on for humans up until around 2010 when FDA funding was cancelled

However in Dec 2019 Prof Baric of University of NC signed an agreement to restart work on an FDA / NIH and Moderna Coronavirus Vaccine program. This was before Covid-19 was formally identified

It is clear that other FDA funded but suspended human Coronavirus Vaccines existed. See SMH link below to Prof N Petrovsky who has received over time $30 million of FDA / Govt vaccine funding

View: https://mobile.twitter.com/LawrenceSellin/status/1365518656998936579



https://www.nbcnews.com/health/health-care/scientists-were-close-coronavirus-vaccine-years-ago-then-money-dried-n1150091
 

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