Reading an article about retroviral and adenoviral vectors used in gene therapy I had a question in mind about usage of SARS-CoV-2 as a viral vector. For a virus to be used as a vector it should show following properties-
PS- sources
•https://www.sciencedirect.com/science/article/abs/pii/S0163725898000205
•https://www.polyplus-transfection.com/blog/article/viral-vectors-for-gene-therapies/
No copyright infringement intended.
- It should be able to replicate inside host
- It should be able to express inside host
- It should avoid immunosurvillance by an infected host
- It should have good genomic capacity for ligation of desired gene
- It should have low cytotoxicity
PS- sources
•https://www.sciencedirect.com/science/article/abs/pii/S0163725898000205
•https://www.polyplus-transfection.com/blog/article/viral-vectors-for-gene-therapies/
No copyright infringement intended.